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KCTD1 Antibody, FITC conjugated

Datasheet
Code CSB-PA744477LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KCTD1 Polyclonal antibody
Uniprot No.
Q719H9
Target Names
KCTD1
Alternative Names
KCTD1 antibody; C18orf5 antibody; BTB/POZ domain-containing protein KCTD1 antibody; Potassium channel tetramerization domain-containing protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human BTB/POZ domain-containing protein KCTD1 protein (1-257AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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KCTD1 Proteins

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Target Background

Function
May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.
Gene References into Functions
  1. results reveal a novel role for Cu(2+) in determining the structure and function of KCTD1 PMID: 27596723
  2. The authors find that the KCTD proteins 5, 6, 9 and 17 bind to Cul3 with high affinity, while the KCTD proteins 1 and 16 do not have detectable binding. PMID: 26334369
  3. KCTD1 functions as a novel inhibitor of Wnt signaling p PMID: 24736394
  4. Mutations in KCTD1 cause scalp-ear-nipple syndrome. PMID: 23541344
  5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  6. indicate the novel function of KCTD1 as the transcriptional repressor for AP-2 family, especially for AP-2alpha PMID: 19115315

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Involvement in disease
Scalp-ear-nipple syndrome (SENS)
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in mammary gland, kidney, brain and ovary.
Database Links

HGNC: 18249

OMIM: 181270

KEGG: hsa:284252

STRING: 9606.ENSP00000408405

UniGene: Hs.526630

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